SOLiD™ System Human (Yoruban) Data Set

Description

• We have sequenced an anonymous individual of African origin using the SOLiD ligation based sequencing assay that enables a unique form of error correction that improves the raw accuracy of the aligned reads to >99.9% allowing us to accurately call SNPs with 2 reads per allele. We collected several billion mate-pair reads yielding ~18X haploid coverage of aligned sequence and close to 300X clone coverage. Over 98% of the reference genome is covered with at least one uniquely placed read and 99.65% spanned by at least one uniquely placed mate-paired clone. We identified over 3.8 million SNPs, 19% of which are novel. Mate-pair data was used to physically resolve haplotype phases of nearly 2/3 of the genotypes obtained, producing phased segments of up to 210 Kb. We detected 229,375 intra-read indels of which half are novel, 5,590 indels between mate-paired reads, 91 inversions and 565 copy number variations. These variants are available here for public use.

Licensing

• This data is being licensed to you under the Applied Biosystems SOLiD™ System Data Use Agreement (Unsupported).  Please read the license in its entirety and ensure that you understand the licensing conditions for use. Your use of this data indicates your acceptance of this licensing agreement. Click on this link to read the licensing agreement.

Support

• This data is being released as "unsupported data" by Applied Biosystems

Download

• Download data files below

   

  File	Description
  Yoruban_var.tar.bz2* 2x25.tar.bz2 2x50.tar.bz2 frag.tar.bz2	Variants in GFF format 25bp mate pair data in match format 50bp mate pair data in match format 50bp fragment data in match format

   

  *These are ftp links with embedded login and may not work in some browsers. The data may be accessed with an ftp client and the following information:

  Server	ftp1.solidsoftwaretools.com
  Username	solidanon
  Password	solidanon1mmoorex
  File	anonymous/yoruban/Yoruban_var.tar.bz2