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Why Galaxy? Developing tools to analyze overwhelming amounts of data generated by next-generation sequencing technologies is no longer the main challenge in biomedical research. Instead the problem lies in making existing tools usable for bench biologists so that they can take full advantage of the data. Galaxy (http://galaxyproject.org) is specifically designed to solve this problem. For experimental biologists, it provides an intuitive and consistent interface for performing sophisticated sequence analyses with minimal effort, regardless of the scale of data involved. For computational tool developers, it makes it easy to integrate existing tools with a modern user interface by writing a simple, concise interface description. For data providers, it features a simple, elegant data access protocol. Thus, Galaxy bridges a critically important gap between data resources, computational tools and users, by making it easy to modernize the interfaces of any existing tool, freeing developers of new tools from the need to develop interfaces from scratch, and facilitating tool interoperability and complex analyses by seamlessly integrating analysis outputs, applications and external data.
Galaxy and AB SOLiD Galaxy is ideally suited for integration of existing command-line driven SOLiD analysis tools. At this moment Galaxy supports mapping of SOLiD colorspace data agianst small genomes with http://galaxyproject.org. In the coming weeks we will be adding QC assessment tools and Velvet assembler ported for use of SOLiD data. SHRiMP package involving these tools will also be provided.
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