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Welcome to the home page for BFAST on Solid Software Tools. BFAST stand for the "Blat-like Fast Accurate Search Tool".
BFAST facilitates the fast and accurate mapping of short reads to reference sequences. Some advantages of BFAST include:
- Speed: enables billions of short reads to be mapped quickly.
- Accuracy: A priori probabilities for mapping reads with defined set of variants.
- An easy way to measurably tune accuracy at the expense of speed.
Specifically, BFAST was designed to facilitate whole-genome resequencing, where mapping billions of short reads with variants is of utmost importance.
BFAST is able to map in both color space and nucleotide space. It uses a full local Smith-Waterman algorithm to score alignment, correcting for color errors, allowing for mutations/variants/SNPs, insertions, and deletions.
Please cite the website "http://genome.ucla.edu/bfast" as well as the accompanying
paper (Nils Homer, Stanley F. Nelson and Barry Merriman. 2008 (Unpublished)). Please
see the accompanying LICENSE for more details on permitted use, proper citation and
other such details.
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| Description |
BFAST facilitates the fast and accurate
mapping of short reads to reference
sequences.
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| Developer Info |
Nils Homer
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| Trove Categorization |
- Development Status: 3 - Alpha
- Intended Audience: Developers,
End Users/Desktop,
Other Audience
- License: Other/Proprietary License
- Operating System: Linux,
MacOS,
POSIX
- Programming Language: C
- Spoken Language: English
- Topic: Bio-Informatics,
Mathematics,
Medical Science Apps.,
Other/Nonlisted Topic,
Software Development
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